Thiamphenicol
Identification
Name Thiamphenicol
Synonyms Methylsulfonyl chloramphenicol
Molecular Formula C12H15Cl2NO5S
Molecular Weight 356.22
CAS Registry Number 15318-45-3
EINECS 239-355-3
White crystal powder
Thiamphenicol (also known as thiophenicol and dextrosulphenidol) is an antibiotic. It is the methyl-sulfonyl analogue of chloramphenicol and has a similar spectrum of activity, but is 2.5 to 5 times as potent. Like chloramphenicol, it is insoluble in water, but highly soluble in lipids. It is used in many countries as a veterinary antibiotic, but is available in China and Italy for use in humans. Its main advantage over chloramphenicol is that it has never been associated with aplastic anaemia.